After you eat or drink, your body breaks down the sugars in your blood and turns it into glucose. The glucose travels through your bloodstream and provides your body with energy. To accomplish this, your pancreas needs to produce a hormone called insulin. In a person with diabetes (diabetes mellitus), the pancreas either produces too little insulin or none at all, or the insulin can’t be used effectively. This allows blood glucose levels to rise while the rest of your cells are deprived of much needed energy. This can lead to a wide variety of problems affecting nearly every part of your body.
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The Effects of Diabetes on the Body :
There are two main types of diabetes. Type 1, also known as juvenile diabetes or insulin-dependent diabetes, is an immune system disorder. In Type 1 diabetes, the patient’s own immune system attacks the insulin-producing cells in the pancreas, destroying the ability to manufacture insulin. People with Type 1 diabetes must take insulin to live. Most people with Type 1 diabetes are diagnosed as children or young adults.
The main problem in Type 2 diabetes is the presence of what is called insulin resistance. In this sort of diabetes, the pancreas starts off robust in its production of insulin. However, cells that need energy don’t respond normally to the usual amounts of insulin. The pancreas has to produce much higher levels of the hormone in order to manage blood glucose levels. Over time, the insulin-producing cells in the pancreas can burn themselves out due to this overproduction. At this point a person with Type 2 diabetes begins to require insulin medication. However, in earlier phases of this more common type of diabetes, the illness can be effectively managed with diet, exercise, and careful monitoring of blood sugars. Some people with Type 2 diabetes may require a variety of oral medications and eventually, as described above, some will eventually need insulin.
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Gestational diabetes is high blood sugar that develops during pregnancy. Most of the time, gestational diabetes can be controlled through diet and exercise, and it typically resolves after the baby is delivered.Common symptoms of diabetes include excessive thirst, frequent urination, and sluggishness. Blood tests will reveal high sugar levels.
Endocrine, Excretory, and Digestive Systems
Your pancreas produces and releases insulin to help make energy out of sugars. If your pancreas produces little or no insulin, or if your body can’t use it, alternate hormones are used to turn fat into energy. This can create high levels of toxic chemicals, including acids and ketone bodies, which may lead to a condition called diabetic ketoacidosis. This is a serious complication of the disease. Symptoms include extreme thirst, excessive urination, and fatigue. Your breath may have a sweet scent that is caused by the elevated levels of ketone bodies in the blood. High blood sugar levels and excess ketones in your urine can confirm diabetic ketoacidosis. Untreated, the condition can lead to loss of consciousness or even death.
Diabetes can damage your kidneys, affecting their ability to filter waste products from your blood. Elevated amounts of protein in your urine (microalbuminuria) may be a sign that your kidneys aren’t functioning properly. Kidney disease related to diabetes is called diabetic nephropathy. This condition doesn’t show symptoms until it advances to later stages. People with diabetes should be evaluated for nephropathy in order to avoid irreversible kidney damage and kidney failure.
Diabetic hyperglycemic hyperosmolar syndrome (HHS) occurs in Type 2 diabetes. It involves very high blood glucose levels but without ketones. Symptoms also include dehydration and loss of consciousness. It usually happens to people whose diabetes is undiagnosed or who have not been able to control their diabetes. It can also be caused by heart attack, stroke, or infection.
High blood glucose levels can make it hard for your stomach to completely empty (gastroparesis). In turn, the delay causes blood glucose levels to rise. Diabetes is the leading cause of gastroparesis. Symptoms include nausea, vomiting, bloating, and heartburn.
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